BEYOND – Biological, Environmental, and Psychosocial Determinants of Psychosis with Longitudinal Evidence from a Large-Scale Ethiopian Study

The project aims to address a major gap in understanding the causes of psychosis in Ethiopia and other LMICs by integrating genetic and environmental factors. It will examine how genetic variation interacts with environmental exposures such as khat use, trauma, food insecurity, and climate-related stress to influence the onset and course of psychosis.

Using a large longitudinal cohort with deep phenotyping and genome-wide data, the study seeks to identify population-specific risk loci and gene–environment interactions. The ultimate goal is to improve etiological models and inform culturally adapted prevention, diagnosis, and intervention strategies for psychosis in African settings.

In collaboration with: Jimma University, Ethiopia

Verantwortliche Personen
Leitung: Kristina Adorjan
Team: Andreas Haas, Laura Oetzel, Ladina Amrein